Wednesday, December 13, 2006

CAT 125 Essay - part 3

This post is part of an on-going series on my CAT 125 project.
Check the introductory post here for more details.


Rise and Fall – The Journey of a Scientist
or where I see myself in 30 years time

(continuing from part 2)

From an undergraduate’s perspective, choosing the right professor to work with is akin to picking a single winning stock from the 3200+ companies listed on NASDAQ to invest your family fortune in – the plethora of options available will definitely overwhelm any newbie. As any stock analyst would advise, doing your homework before you invest any dollar is critical to getting good returns, even if the stock is widely recommended by everyone and their stockbroker. Big universities like UCSD hold hundreds of researchers in biology alone, each with wide-ranging abilities, areas of focus, and successes. Newcomers to the area, from fresh undergraduates to aspiring graduate students, have to attempt to sift out the genius from the mediocre and the inspirational leader from the slave driver. Big names famous globally for ground-breaking discoveries are often also infamous locally for demanding back-breaking work all the time from everyone. I decided to hit the grapevines to in search for the truth...

And I was shocked (and sorely disappointed) as a result. Insiders relate that Prof Q’s eye bags stemmed not solely from Toll, but mainly from worrying about the future of the lab he spent half a lifetime building up – Prof Q had failed to secure a critical grant that would have provided the lab enough money to last the next two years. Grants – judge, jury and executioner all rolled in one – provide much-needed capital to purchase daily research expendables and to pay the salary of everyone in the lab: from lab technicians, graduate students to post-doctoral researchers. Losing funding is academia’s equivalent of getting an F on your undergraduate transcript. On first glance, the rejection may just seem to be a small pothole in a long career. On a closer look, however, the rejection is also applied to the research problem submitted with the grant application that an investigator may have staked his future on investigating. Just as an F on an undergraduate transcript directly predicts a wrecked GPA that needs salvaging and a broken dream of attending medical school, the loss of funding in a lab almost directly implicates loss of job security, a broken reputation and an uncertain future for everyone related.

That weekend was simply terrible for me and my conscience. A part of me strongly supported working for Prof Q, a show of solidarity and support that he might need at this critical moment. And yet, the devil’s constant reminders of my own dreams of a bright future for myself seemed to all but hinge on my one decision at this moment. The long, painful weekend was totally wasted in an endless internal conflict, debating the pros and cons of possible outcomes. In the end, logic won over emotions (as it always does in everything I do): I would slink silently away like a coward and seek refuge in another lab. But before I could do that, I (unfortunately) had to face Prof Q, one last time, to return his lab keys before I could disappear from his life forever. That encounter turned out to be brief, and I honestly have no recollections of what exactly happened. All I know is that I successfully rid myself of the keys, and life goes on.

(to be continued...)

Posts from the CAT 125 Series
- Written Abstract
- Visual Abstract
- Essay part 1
- Essay part 2
- Essay part 3
- Essay part 4
- Essay part 5 (end)

Sunday, December 10, 2006

CAT 125 Essay - part 2

This post is part of an on-going series on my CAT 125 project.
Check the introductory post here for more details.


Rise and Fall – The Journey of a Scientist
or where I see myself in 30 years time

(continuing from part 1)

The story first began two weeks prior when I started looking for an undergraduate research position in a biomedical research laboratory. My passion to uncover new understandings of the world around us as well as the need to insulate myself from the increasingly religious-fanatic world made a future in research a given. Biomedical research was also the latest “in-thing” for new and aspiring scientists of the new millennium, and I was terribly keen not to miss the boat(load of funding).

Prof Q is a Professor of Biology who studies the Toll signal transduction pathway in the fruit fly. Toll is an important protein involved in the regulation of the innate immune response against microbial infection and ensures the correct formation of the dorsoventral axis in the fly embryo. Prof Q’s research utilizes many fundamental techniques which a newbie to the field (like me) can clearly benefit from. He is also known to be a friendly and responsible leader to his team of researchers. But perhaps more importantly, Prof Q holds an impressive CV that boasts numerous awards, a Harvard-MIT education and directorship for the Center for Molecular Genetics. A research stint in his lab would not only provide me with a wealth of relevant research experience, but tagging his big name to my graduate school applications will also seriously enhance my personal prospects. Following him in his footsteps was the way forward, I thought.

Prof Q had promptly replied to my email request and invited me to his office for an interview the Friday before. I remember being awed by his rapid response and openness to taking bumbling undergraduates into his lab. (Less than half of the professors I contacted bothered responding to my email, and only a handful had vacancies for undergraduates.) During the interview, as Prof Q chatted with me about his research and my interests, I scrutinized his big, heavy-set eyes with their accompanying dark eye bags and deep wrinkles. I could see my future eyes reflected in his. “Toll must have taken a toll on his sleep,” I thought. But before I could get too smug with my own ingenuity, Prof Q promptly handed me the keys to his lab without much ado. I was shocked, to say the least, of the brevity of the exchange and the immense trust he just left in my hands. At long last, I was about to embark on my life-long journey to become a well-respected, omniscient scientist who will change world history with my keen insights into age-old dilemmas. I was on my journey to be a successful scientist, just like Prof Q.

(to be continued...)

Posts from the CAT 125 Series
- Written Abstract
- Visual Abstract
- Essay part 1
- Essay part 2
- Essay part 3
- Essay part 4
- Essay part 5 (end)

tired

3 days to midterm. 3 days to start and finish studying. 10 chapters= 250 chapters to read, understand, memorize. how fun.

Thursday, December 07, 2006

CAT 125 Essay - part 1

This post is part of an on-going series on my CAT 125 project.
Check the introductory post here for more details.


Rise and Fall – The Journey of a Scientist
or where I see myself in 30 years time

Bonner Hall must have been an imposing building to the throngs of undergraduates milling to and from Revelle College when it was first completed 40 years ago. This “state-of-the-art” 4-storey tall building has the capacity to house over 300 scientists in 20 biomedical research laboratories, including 5 conferences rooms for hosting scientific collaborations, 3 undergraduate teaching labs for upper division biology classes and a fly food preparation facility to support the many labs working with Drosophila melanogaster, the ever popular (and ever stinking) fruit fly.

And Bonner Hall is where the story developed about a year ago. I found myself that Monday afternoon standing silently in front of the glass doors leading into the north-east wing of Bonner Hall 4th floor, staring but not seeing the few wandering fruit flies on the other side of the door. The flies circled aimlessly for their escape from the building, where the acrid smell of fly food mingled with the sickly sweet smell of sticky death traps[1]. My thoughts drifted briefly to the possible fates of a fruit fly born and bred in a laboratory. Unwillingly trapped in fly heaven from birth (or fly hell, depending on how you look at it), these flies are supplied with endless food, deprived of ever knowing what a spider (its natural predator) looks like, and simply live out its natural life cycle eating and mating. Occasionally though, they might be irradiated with UV, treated with chemical mutagens, mated with less-than-ideal partners, dissected for observation, or more often than not, simply gassed and discarded with our everyday trash. Our common fruit fly – a species dedicated to research for the betterment of mankind. But the significance (and irony) of the deaths of millions of their pesky kin paled in comparison to the awkward situation I unwittingly set myself up into. As I gazed down the empty corridor that led to Prof Q’s office, I racked my mind for the most respectful, least embarrassing, and most roundabout way to inform Prof Q that I simply did not wish to start work in his lab anymore.

(to be continued...)

[1]
A jar with insides coated with diluted honey or vegetable oil inverted over crushed bananas makes a cheap and effective solution to trap escaped flies.

Posts from the CAT 125 Series
- Written Abstract
- Visual Abstract
- Essay part 1
- Essay part 2
- Essay part 3
- Essay part 4
- Essay part 5 (end)

Tuesday, December 05, 2006

CAT 125 Visual Abstract



This post is part of an on-going series on my CAT 125 project.
Check the previous post here for more details.

Posts from the CAT 125 Series
- Written Abstract
- Visual Abstract
- Essay part 1
- Essay part 2
- Essay part 3
- Essay part 4
- Essay part 5 (end)

Sunday, December 03, 2006

CAT 125 Written Abstract

Over the next few days, I will be serializing my CAT Practicum Writing project here. This Practicum Writing class has been the bane of my college career, and has tormented me since I first took it last Apr (Spring 2005). I have finally finished the essay, and am glad that it is finally of decent quality which I dare submit. The main Essay is not as polished as I would like, and does not contain many related thoughts that I originally intend to incorporate. But for a major essay which I started writing merely a week before the due date (we were given ten), I'm happy with the way it turned out. The first part of the project, a Written Abstract, is appended below. It will be followed over the following days by a Visual Abstract and The Essay. Critical comments on my work are encouraged, but similar random thoughts on the subject matter are welcomed too.

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CAT 125 Written Abstract:
Rise and Fall – The Journey of a Scientist

or where I see myself in 30 years time

As a senior graduating with a relatively successful transcript and considerable research experience, it is easy to spend the final stretch of my short college career trapped in the mindless rat race for the last few ‘A’s, miring in mundane graduate school applications, or just day-dreaming of the successful self and the rosy future. But the complete immersion into the academic research environment in the past year opened my eyes and my mind to the “real” world, where words like “career”, “salary”, “job security” and “future” take on a whole new meaning. Many fresh college graduates enter the “real” world with “unreal” expectations and end up disillusioned when their fairy tales fail to materialize. The “real” world of science is no different. Witnessing the rise and fall of the people working beside you is the most direct and efficient way to learn that lesson, and to learn it well.

This essay is a personal recollection and reflection on the fantastic personas I have had the honor to interact with over the last one year. These experiences provided me with plenty of food for thought about the Ultimate Question of Life, the Universe, and Everything. This essay hopes to portray, subtly, the importance of stepping back and embracing the big picture. Of understanding why we do what we do. So that we can peacefully live out the rest of our lives, never regretting our decision to embark on a particular journey.


To glorious Science and her humble servants,

November 29, 2006

Posts from the CAT 125 Series
- Written Abstract
- Visual Abstract
- Essay part 1
- Essay part 2
- Essay part 3
- Essay part 4
- Essay part 5 (end)